| Customization: | Available |
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| CAS No.: | 22900-11-4 |
| Formula: | C12h21no9 |
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Research Applications:Neu5Ac-Me is a cornerstone in biochemical and molecular biology research, especially for unraveling the intricate mysteries of glycobiology (the exploration of carbohydrate structures, functions, and biological roles) and glycomics (the comprehensive study of carbohydrate components within living organisms).
This compound is instrumental in synthesizing sialylated compounds and understanding the complex interactions between sialic acids and lectins (proteins that bind carbohydrates) or pathogens (including viruses and bacteria) that engage with sialic acid residues on host cells. The methyl ester form of N-acetylneuraminic acid (NANA) offers enhanced handling stability, making it an invaluable asset for chemical and enzymatic research.
Potential Use in Drug Development: Given that sialic acids play pivotal roles in essential cellular processes, N-acetylneuraminic acid methyl ester holds promise for therapeutic innovations. Investigations have explored sialic acid derivatives for their potential to modulate immune responses, thwart infections by impeding viral adhesion, and target specific cancerous cells. For instance, the binding capability of viruses such as influenza or enteric pathogens (including E. coli and Norovirus) to attach to sialic acid residues on host cells is crucial for infection. By altering or inhibiting these interactions, sialic acid derivatives may deliver antiviral or antimicrobial benefits.
Synthesis: Neu5Ac-Me is synthesized through the chemical esterification of N-acetylneuraminic acid (NANA) using methylating agents. This modification alters NANA's chemical attributes, enhancing its solubility, stability, and reactivity in specific chemical processes.
Stability and Application: N-Acetylneuraminic acid methyl ester (Neu5Ac-Me) exhibits greater stability compared to free NANA, which is susceptible to degradation. Consequently, Neu5Ac-Me is ideal for settings and applications where stability is paramount, such as in pharmaceutical formulations and biochemical testing.
| Test Index | Standard Provision | Result |
| Appearance | White or Similar White Crystalline Powder | White Powder |
| Smell | Odorless | Odorless |
| Assay(Converted on Dry Basis) | >99% | 99.65% |
| Purity(by HPLC) | >99% | 99.45% |
| optical rotation | -30°~ -34° | -32.1° |
| Heavy Metal | <10ppm | <10ppm |
| Fe | <5ppm | Not Detected |
| Pb | <0.1mg/kg | Not Detected |
| Hg | <0.3mg/kg | Not Detected |
| As | <0.3mg/kg | Not Detected |
| Cr | <0.3mg/kg | 0.088 |
| Transmittance | ≥99% | 99.5% |
| PH | 1.8-2.3 | 2.13 |
| Water Content | ≤1.0% | 0.25% |
| Ash | ≤1.0% | 0.46% |
| Ethanol residue | <0.5% | 0.15% |
| Loss on drying | ≤0.5% | 0.32% |
| Total plate count | <100CFU/g | <10CFU/g |
| Yeast and Molds | <10CFU/g | <10CFU/g |
| Number of Coliforms | Not Detectable | Not Detected |
| Staphylococcus Aureus | Not Detectable | Not Detected |
| Salmonella Count | Not Detectable | Not Detected |
| Listeria Monocytogenes | Not Detectable | Not Detected |
| Cronobacter sakazakii | Not Detectable | Not Detected |
| Bacillus Cereus | <50CFU/g | <10CFU/g |
| Dibutyl Phthalate | Not Detectable | Not Detected |
| Conclusion:The products Conforms to in-house | ||
Shipping:At Zhejiang Zhengshuo Biotechnology Co., Ltd., we ensure that your product reaches you swiftly and safely with our efficient logistics strategies. We offer: DHL / FedEx / EMS / By Air
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