N-Acetylneuraminic Acid Dihydrate Pharmaceutical Grade for Research Use CAS50795-27-2

Product Details
Customization: Available
CAS No.: 50795-27-2
Formula: C11h23no11
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  • N-Acetylneuraminic Acid Dihydrate Pharmaceutical Grade for Research Use CAS50795-27-2
  • N-Acetylneuraminic Acid Dihydrate Pharmaceutical Grade for Research Use CAS50795-27-2
  • N-Acetylneuraminic Acid Dihydrate Pharmaceutical Grade for Research Use CAS50795-27-2
  • N-Acetylneuraminic Acid Dihydrate Pharmaceutical Grade for Research Use CAS50795-27-2
  • N-Acetylneuraminic Acid Dihydrate Pharmaceutical Grade for Research Use CAS50795-27-2
  • N-Acetylneuraminic Acid Dihydrate Pharmaceutical Grade for Research Use CAS50795-27-2
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  • Overview
  • Product Description
  • Detailed Photos
  • Function
  • Application
  • Product Parameters
  • Certifications
  • Company Profile
  • Packaging & Shipping
Overview

Basic Info.

Model NO.
50795-27-2
Packaging Material
Paper
Storage Method
Normal
Shelf Life
>12 Months
Nutrient Composition
Mineral
Resource
Natural
The content of active substances
>90%
Appearance
White Powder
Smell
Odorless
Assay(Converted on Dry Basis)
99.65%
Optical Rotation
-32.1°
Heavy Metal
<10ppm
Transport Package
1kg/Bag; 25kg/Carton; 50kg/Drum
Specification
>99%
Trademark
Zhengshuo Biotech
Origin
China
HS Code
2932999099
Production Capacity
10 Tons/Year

Product Description

Product Description

N-Acetylneuraminic Acid Dihydrate, also known as Neu5Ac or NANA, is a cornerstone compound celebrated for its indispensable and multifaceted contributions to the realm of biology. Embark on a comprehensive exploration with us to discover its crucial roles and the vast spectrum of applications that underscore its importance and impact in the spheres of scientific research and pioneering innovation.
 
Detailed Photos

N-Acetylneuraminic Acid Dihydrate Pharmaceutical Grade for Research Use CAS50795-27-2

Function

Cellular Recognition: Neu5Ac, famously known as N-Acetylneuraminic Acid, is indispensable in cellular biology. It enriches glycoproteins and glycolipids that beautifully adorn cell surfaces, acting as a crucial recognition molecule. This remarkable compound orchestrates the fascinating interactions between cells, playing a key role in immune response mechanisms and the complex intricacies of cell adhesion.
Viral Infection: Neu5Ac is a beacon of insight in the realms of viral infections. Especially notable are its interactions with influenza viruses, which smartly target and bind to Neu5Ac on host cells to advance their infectious agenda. Delving into these viral-protein and Neu5Ac interactions provides groundbreaking opportunities for revolutionary antiviral strategy development, shining a hopeful light in the battle against viral epidemics.
Brain Development: In the captivating world of neuroscience, Neu5Ac is vital for brain development and proper functionality. It is a fundamental building block in the formation of gangliosides, which are abundantly found in neuronal membranes. These gangliosides are crucial for cell signaling pathways and provide substantial protection to neurons, emphasizing Neu5Ac's essential role in maintaining cognitive health and offering neuroprotection.
Glycosylation: Neu5Ac serves as a cornerstone in glycosylation processes, functioning as an essential precursor molecule where sugars are seamlessly affixed to proteins or lipids. This biochemical modification is critical for supporting the stability, efficiency, and recognition of numerous biomolecules, thereby safeguarding cellular integrity and activity.
Application

Research Applications:Neu5Ac-Me stands as a cornerstone in the unparalleled world of biochemical and molecular biology research, significantly contributing to the advancement of glycobiology (which unravels the intricate structure, function, and biological significance of carbohydrates) and glycomics (which explores the vast carbohydrate landscapes within living organisms with precision).
It is indispensable in the synthesis of pivotal sialylated compounds and crucial for exploring the dynamics between sialic acids and lectins (proteins with precise carbohydrate-binding abilities) or pathogens (like viruses and bacteria) that engage with sialic acid residues on host cells. The methyl ester form of NANA provides superior handling and exceptional stability in laboratory settings, making it an invaluable resource for both chemical and enzymatic studies.
Potential Use in Drug Development:Recognizing the essential role sialic acids play in diverse cellular activities, N-acetylneuraminic acid methyl ester emerges as a promising frontier in the realm of therapeutics. Current research focuses on exploiting sialic acid derivatives to modulate immune responses, prevent infections by obstructing viral adhesion, and potentially disrupt specific cancer cell mechanisms.For instance, the capability of viruses like the influenza virus or enteric pathogens (including E. coli and Norovirus) to bind to sialic acid residues on host cells is central to their infection strategy. By refining or averting these essential interactions, sialic acid derivatives offer the potential for revolutionary antiviral or antimicrobial advancements.
Synthesis:Neu5Ac-Me is artfully synthesized through the intricate chemical esterification process of N-acetylneuraminic acid (NANA) utilizing methylating agents. This chemical transformation enhances NANA's properties, improving aspects like solubility, stability, and reactivity in select chemical reactions.
Stability and Application:N-Acetylneuraminic acid methyl ester (Neu5Ac-Me) exhibits remarkable stability compared to free NANA, which is prone to degradation. Therefore, Neu5Ac-Me becomes essential in applications demanding consistent stability, such as drug formulations or intensive biochemical assays.

Product Parameters
Test Index Standard Provision Result
Appearance White or Similar White Crystalline Powder White Powder
Smell Odorless Odorless
Assay(Converted on Dry Basis) >99% 99.65%
Purity(by HPLC) >99% 99.45%
optical rotation -30°~ -34° -32.1°
Heavy Metal <10ppm <10ppm
Fe <5ppm Not Detected
Pb <0.1mg/kg Not Detected
Hg <0.3mg/kg Not Detected
As <0.3mg/kg Not Detected
Cr <0.3mg/kg 0.088
Transmittance ≥99% 99.5%
PH 1.8-2.3 2.13
Water Content ≤1.0% 0.25%
Ash ≤1.0% 0.46%
Ethanol residue <0.5% 0.15%
Loss on drying ≤0.5% 0.32%
Total plate count <100CFU/g <10CFU/g
Yeast and Molds <10CFU/g <10CFU/g
Number of Coliforms Not Detectable Not Detected
Staphylococcus Aureus Not Detectable Not Detected
Salmonella Count Not Detectable Not Detected
Listeria Monocytogenes Not Detectable Not Detected
Cronobacter sakazakii Not Detectable Not Detected
Bacillus Cereus <50CFU/g <10CFU/g
Dibutyl Phthalate Not Detectable Not Detected
Conclusion:The products Conforms to in-house
Certifications

N-Acetylneuraminic Acid Dihydrate Pharmaceutical Grade for Research Use CAS50795-27-2

Company Profile

N-Acetylneuraminic Acid Dihydrate Pharmaceutical Grade for Research Use CAS50795-27-2N-Acetylneuraminic Acid Dihydrate Pharmaceutical Grade for Research Use CAS50795-27-2

Packaging & Shipping

Shipping:Shipping Method: DHL / FedEx / EMS / By Air

  1. For shipments under 50kgs, we strongly advocate the use of International Express with FedEx or DHL. Experience the ease of our Delivered-at-Place (DAP) service, crafted to ensure a smooth and hassle-free delivery journey.
  2. For packages weighing less than 200kgs, air transportation stands as our favored option. Enjoy the versatility of either picking up your package yourself or choosing our dependable door-to-door service, all designed with your convenience in mind.
  3. For more substantial shipments up to 2500kgs, sea transportation emerges as our recommended choice. Opt for customer pick-up or savor the ease of our full-service door-to-door option.or savor the ease of our full-service door-to-door option.N-Acetylneuraminic Acid Dihydrate Pharmaceutical Grade for Research Use CAS50795-27-2N-Acetylneuraminic Acid Dihydrate Pharmaceutical Grade for Research Use CAS50795-27-2

FAQ
1. What types of ingredients do you supply?
We proudly provide a vast and varied array of ingredients, meticulously curated to meet a wide spectrum of formulation demands. Our portfolio includes nutraceutical ingredients, cosmetic ingredients, food ingredients, and pharmaceutical intermediates.

2. How can I obtain a sample?
Securing a sample is uncomplicated. Simply take care of the sample cost and express fee, which we will gladly reimburse with your initial purchase, offering you a risk-free opportunity to evaluate our products.

3. Do you offer OEM & ODM services?
Indeed, we are delighted to provide OEM & ODM services, backed by our expert R&D team, to craft solutions that precisely match your unique requirements and expectations.

4. What quality standards do your ingredients comply with?
Be assured, our ingredients meet rigorous industry-standard quality and safety criteria. We offer comprehensive compliance and relevant documentation, including Certificates of Analysis, as needed.


5. What is your lead time?
Our standard lead time ranges from 7-10 working days, ensuring a swift and efficient service. Should you have special requirements, please engage with us to customize the timeline to better fit your needs.

6. What are your payment terms?
We offer flexibility with payment methods, accepting various forms such as T/T, Paypal, Western Union, and additional negotiable options tailored to your preferences.

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