Customization: | Available |
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CAS No.: | 122628-50-6 |
Formula: | C14h6n2o8 |
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Pyrroloquinoline quinone is short for PQQ. This cutting-edge prosthetic group is renowned for its multifaceted therapeutic potential, playing a crucial role in the treatment of heart disease, neurological disorders, liver protection, and the maintenance of mitochondrial health.
Pyrroloquinoline quinones are abundantly found in prokaryotes, plants, and mammals. These remarkable compounds function not only as key prosthetic groups for various enzymes but also excel in the transfer of electrons, protons, and chemical groups during enzymatic reactions. Furthermore, they possess the ability to stimulate the growth of microorganisms, plant germination, and overall plant development.
1. Shield the heart from oxidative damage
PQQ's cardioprotective effects are intricately linked to its prowess in neutralizing free radicals. By scavenging reactive oxygen species (ROS) generated during hypoxia-reperfusion events, PQQ substantially curtails the release of lactate dehydrogenase in the heart. Additionally, with the assistance of flavin reductase, PQQ's catalytic byproducts can mitigate the peroxidation state of hemoglobin, effectively safeguarding the myocardium from the detrimental impacts of hypoxia and reperfusion.
2. Guard against liver damage
PQQ, when pre-administered in specific doses to the abdominal cavity, offers robust protection against experimental liver damage in rats induced by toxins such as carbon tetrachloride (CCl), galactosamine, and sulfide acetamide. By curbing ROS production incited by hepatotoxic substances, PQQ significantly reduces serum bilirubin glutamic pyruvic transaminase (GPT) and lactate dehydrogenase levels, effectively preventing liver cell necrosis without adversely affecting conventional biochemical parameters in rats, such as blood sugar and blood urea nitrogen.
3. Foster nerve growth and fortify the nervous system
Nerve *** (NGF) stands out as the pioneer among neurotrophic factors, extensively studied for its dual role in neuronal nutrition and protection. NGF is instrumental in the growth, development, differentiation, regeneration, and specific functional expression of both central and peripheral neurons. In vitro experiments demonstrate that PQQ can effectively stimulate L-M cells and Schwann cells to produce NGF, reinforcing its pivotal position in neuroprotection.
4. Counteract acetaldehyde poisoning
Acetaldehyde, a toxic intermediate metabolite of alcohol in animals, poses significant risks, especially for individuals with acetaldehyde dehydrogenase gene mutations, leading to enzyme insufficiency and subsequent acetaldehyde accumulation post-drinking. This results in mild poisoning reactions such as redness, flushing, and dizziness. PQQ offers potential in counteracting these adverse effects.
Antioxidant and free radical scavenging: Harness the powerful potential of our PQQ Pyrroloquinoline Quinone Disodium Salt Antioxidant White Powder, designed to combat oxidative stress and neutralize harmful free radicals, preserving your body's health and vitality.
Cellular and mitochondrial health (promoting energy metabolism and mitochondrial regeneration): Experience revitalized energy and mitochondrial rejuvenation with our product's unique formula, crafted to enhance cellular health and boost your energy metabolism for a more vibrant you.
Cognitive function and brain health (memory, learning and neuroprotection): Elevate your cognitive function and safeguard your brain health with our cutting-edge antioxidant, supporting memory retention, learning capabilities, and offering robust neuroprotective benefits for a sharper mind.
Energy metabolism and physical recovery: Recharge your body and optimize energy metabolism for peak performance and rapid physical recovery, ensuring you're always ready to tackle life's challenges with vigor.
Cardiovascular health (lowering blood lipids, anti-inflammatory): Nurture your heart with our antioxidant's cardiovascular benefits, expertly formulated to lower blood lipids and deliver potent anti-inflammatory effects for a healthier, more resilient cardiovascular system.
Anti-aging and slowing the aging process: Embrace the journey of graceful aging with our innovative product, designed to slow the aging process, keeping you feeling youthful and vibrant.
Immune system support: Fortify your immune defenses with our PQQ Pyrroloquinoline Quinone Disodium Salt Antioxidant, offering robust support to keep your immune system strong and resilient.
Liver health: Promote optimal liver function and detoxification with the protective benefits of our antioxidant, aiding in maintaining comprehensive liver health.
As a nutritional supplement, improve health: Integrating seamlessly into your daily regimen, this nutritional supplement elevates overall health, empowering you to lead a balanced and enriched lifestyle.
Diabetes research (blood sugar management): Explore its promising potential in diabetes research, particularly in managing blood sugar levels, paving the way for innovative health solutions.
Test Index | Standard Provision | Result |
Appearance | White or Similar White Crystalline Powder | White Powder |
Smell | Odorless | Odorless |
Assay(Converted on Dry Basis) | >99% | 99.7% |
Purity(by HPLC) | >99% | 99.45% |
optical rotation | -30°~ -34° | -32.1° |
Heavy Metal | <10ppm | <10ppm |
Fe | <5ppm | Not Detected |
Pb | <0.1mg/kg | Not Detected |
Hg | <0.3mg/kg | Not Detected |
As | <0.3mg/kg | Not Detected |
Cr | <0.3mg/kg | 0.088 |
Transmittance | ≥99% | 99.5% |
PH | 1.8-2.3 | 2.13 |
Water Content | ≤1.0% | 0.25% |
Ash | ≤1.0% | 0.46% |
Ethanol residue | <0.5% | 0.15% |
Loss on drying | ≤0.5% | 0.32% |
Total plate count | <100CFU/g | <10CFU/g |
Yeast and Molds | <10CFU/g | <10CFU/g |
Number of Coliforms | Not Detectable | Not Detected |
Staphylococcus Aureus | Not Detectable | Not Detected |
Salmonella Count | Not Detectable | Not Detected |
Listeria Monocytogenes | Not Detectable | Not Detected |
Cronobacter sakazakii | Not Detectable | Not Detected |
Bacillus Cereus | <50CFU/g | <10CFU/g |
Dibutyl Phthalate | Not Detectable | Not Detected |
Conclusion:The products Conforms to in-house |
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