| Customization: | Available |
|---|---|
| CAS No.: | 22900-11-4 |
| Formula: | C12h21no9 |
|
Still deciding? Get samples of $ !
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
Research Applications:Neu5Ac-Me stands as a pivotal agent in the vast landscapes of biochemical and molecular biology exploration, acting as a foundational element in the advanced study of glycobiology (a sophisticated discipline delving into the architecture, functionality, and biological significance of carbohydrates) and glycomics (the exhaustive analysis of carbohydrate constituents within living organisms).
It is indispensable for synthesizing sialylated compounds and probing the intricate dynamics between sialic acids and lectins (specialized carbohydrate-recognizing proteins) or pathogens (including viruses and bacteria) that interact with sialic acid residues present on host cells. The methyl ester version of NANA is frequently chosen for its simplicity in handling and superior stability in laboratory environments, making it an invaluable component for both chemical and enzymatic research endeavors.
Potential Use in Drug Development:Recognizing that sialic acids are integral to a multitude of crucial cellular functions, N-acetylneuraminic acid methyl ester exudes exciting therapeutic potential. Preliminary studies investigate the application of sialic acid derivatives in modulating immune responses, treating infections by inhibiting viral binding, and even honing in on specific cancer cells.For example, the process by which viruses such as influenza or enteric pathogens (like E. coli or Norovirus) adhere to sialic acid residues on host cells is pivotal to the infection mechanism. By disrupting or preventing these connections, sialic acid derivatives may provide notable antiviral or antimicrobial advantages.
Synthesis:Neu5Ac-Me is crafted through the chemical esterification of N-acetylneuraminic acid (NANA) utilizing methylating agents. This process can alter the chemical properties of NANA, including its solubility, stability, and reactivity in a range of chemical reactions.
Stability and Application:N-Acetylneuraminic acid methyl ester (Neu5Ac-Me) typically showcases greater stability than free NANA, which is prone to degradation. Therefore, Neu5Ac-Me proves beneficial in scenarios where stability is critical, such as in pharmaceutical formulations or complex biochemical assays.
| Test Index | Standard Provision | Result |
| Appearance | White or Similar White Crystalline Powder | White Powder |
| Smell | Odorless | Odorless |
| Assay(Converted on Dry Basis) | >99% | 99.65% |
| Purity(by HPLC) | >99% | 99.45% |
| optical rotation | -30°~ -34° | -32.1° |
| Heavy Metal | <10ppm | <10ppm |
| Fe | <5ppm | Not Detected |
| Pb | <0.1mg/kg | Not Detected |
| Hg | <0.3mg/kg | Not Detected |
| As | <0.3mg/kg | Not Detected |
| Cr | <0.3mg/kg | 0.088 |
| Transmittance | ≥99% | 99.5% |
| PH | 1.8-2.3 | 2.13 |
| Water Content | ≤1.0% | 0.25% |
| Ash | ≤1.0% | 0.46% |
| Ethanol residue | <0.5% | 0.15% |
| Loss on drying | ≤0.5% | 0.32% |
| Total plate count | <100CFU/g | <10CFU/g |
| Yeast and Molds | <10CFU/g | <10CFU/g |
| Number of Coliforms | Not Detectable | Not Detected |
| Staphylococcus Aureus | Not Detectable | Not Detected |
| Salmonella Count | Not Detectable | Not Detected |
| Listeria Monocytogenes | Not Detectable | Not Detected |
| Cronobacter sakazakii | Not Detectable | Not Detected |
| Bacillus Cereus | <50CFU/g | <10CFU/g |
| Dibutyl Phthalate | Not Detectable | Not Detected |
| Conclusion:The products Conforms to in-house | ||
Shipping: Shipping Methods: With DHL, FedEx, EMS, or By Air services at your disposal, rest assured of a swift and dependable delivery process.
){kind=link}